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Buccal smear

Contents of this page:

Illustrations

Throat anatomy
Throat anatomy
Buccal  smear
Buccal smear

Alternative Names    Return to top

Sex chromatin test

Definition    Return to top

A buccal smear (pronounced "buckle") is the painless removal of a sample of cells from the lining of the mouth (inside of the cheek) for study.

How the Test is Performed    Return to top

The health care provider will gently scrape the inside of the cheek with a small spatula to collect cells for testing.

How to Prepare for the Test    Return to top

Rinse and wash the mouth as instructed.

How the Test Will Feel    Return to top

You will feel a scraping sensation as cells are removed from the cheek.

Why the Test is Performed    Return to top

The procedure is used to obtain cells for chromosome and DNA analysis,most often for genetic testing. The International Olympic Committee adopted the test many years ago to help detect male imposters among female athletes. When the test is used in this way, it's called the sex chromatin test. This method may also help establish the sexual identity of newborns.

Risks    Return to top

There are no risks.

Update Date: 11/4/2008

Updated by: Frank A. Greco, M.D., Ph.D., Director, Biophysical Laboratory, The Lahey Clinic, Burlington, MA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

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