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Alternative Names Return to topExtrinsic allergic alveolitis; Farmer's lung; Mushroom picker's disease; Humidifier or air-conditioner lung; Bird breeder's lung
Definition Return to top
Hypersensitivity pneumonitis is inflammation of the lungs due to breathing in a foreign substance, usually certain types of dust, fungus, or molds.
Causes Return to top
Hypersensitivity pneumonitis usually occurs in those who work in places where there are high levels of organic dusts, fungus, or molds. For example, farmer's lung is the most common type of hypersensitivity pneumonitis. Repeated or intense exposure to dust from moldy hay, straw, and grain can lead to lung inflammation and acute lung disease. Over time, this acute condition may turn into long-lasting (chronic) lung disease.
The condition may also result from fungus present in humidifiers, heating systems, and air conditioners found in homes and offices. Exposure to certain bird droppings (for example, among bird owners) can also lead to hypersensitivity pneumonitis.
Symptoms Return to top
Symptoms of acute hypersensitivity pneumonitis may occur 4 - 6 hours after you have left the area where the foreign substance is found. These symptoms may include:
Symptoms of chronic hypersensitivity pneumonitis may include:
Exams and Tests Return to top
Your doctor may hear abnormal lung sounds called crackles (rales) when listening to your chest with a stethoscope.
Lung changes due to chronic hypersensitivity pneumonitis may be seen on chest x-ray. Other tests may include:
Treatment Return to top
First, the foreign substance must be identified. Treatment involves avoiding this substance in the future. Some people may need to change jobs if they cannot avoid the substance at work.
If you have a chronic form of this disease, your doctor will give you glucocorticoids (powerful anti-inflammatory medicines).
Outlook (Prognosis) Return to top
Most symptoms go away when you avoid or limit your exposure to the material that caused the problem.
Possible Complications Return to top
The chronic form of this disease may lead to pulmonary fibrosis (a scarring of the lung tissue that often is not reversible).
When to Contact a Medical Professional Return to top
Call your health care provider if you develop symptoms of hypersensitivity pneumonitis.
Prevention Return to top
The chronic form can be prevented by avoiding the material that causes the lung inflammation.
References Return to top
Hoppin JA, Umbach DM, Kullman GJ, et al. Pesticides and other Agricultural Factors Associated with Self-reported Farmer's lung among Farm Residents in the Agricultural Health Study. Occup Environ Med. 2006 Dec 20;[Epub ahead of print].
Lacasse Y, Cormier Y. Hypersensitivity pneumonitis. Orphanet J Rare Dis. 2006 Jul 3;1:25.Update Date: 4/24/2009 Updated by: Allen J. Blaivas, DO, Clinical Assistant Professor of Medicine UMDNJ-NJMS, Attending Physician in the Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Veterans Affairs, VA New Jersey Health Care System, East Orange, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.