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Alternative Names Return to topCulture - amniotic fluid; Culture - amniotic cells
Definition Return to top
Amniocentesis is a test during pregnancy that removes a small amount of fluid from the sac around the baby to look for birth defects and chromosome problems.
How the Test is Performed Return to top
The health care provider will find the exact location of the baby, usually by ultrasound (see pregnancy ultrasound).
The skin of the abdomen is scrubbed. A numbing medication (anesthetic) may be applied to the skin, or a local anesthetic may be injected into the skin.
A long, thin needle is inserted through the abdomen and into the uterus. A small amount of fluid is taken from the fluid-filled sac that surrounds the fetus.
How to Prepare for the Test Return to top
This test is done on the same day -- you will not need to stay overnight in the hospital. You must sign a consent form. Your bladder must be full for the ultrasound. There are no food or drink restrictions.
You may need to provide a blood sample to determine your blood type and Rh factor. You may get an injection of a medication called Rhogam if you are Rh negative.
How the Test Will Feel Return to top
If an anesthetic is used, you may feel a sharp, stinging sensation for a few seconds. When the needle enters the amniotic sac, you may feel a sharp pain lasting a few seconds.
Some women feel pressure in the lower abdomen when the fluid is pulled out. After the procedure, you may have some minor cramping.
Why the Test is Performed Return to top
The test can find chromosome problems such as:
Later on in a pregnancy, the test may be used to find problems such as:
Late in the pregnancy, this test can determine whether the baby's lungs are developed.
Normal Results Return to top
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean Return to top
Amniocentesis can be used to diagnose a large number of gene and chromosome problems in the baby. In addition, it can help diagnose the severity of:
DNA testing is available for many diseases. New diseases are being added to this list as genetic research advances. Ask your obstetrician or geneticist if you have a question about a specific disease.
Risks Return to top
Risks are minimal, but may include:
This test is typically done when a problem is suspected, so the benefits outweigh the risks.
Considerations Return to top
There may be alternatives to the amniocentesis. Discuss these other tests with your health care provider.Update Date: 2/19/2008 Updated by: Peter Chen, MD, Department of Obstetrics & Gynecology, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.